Testosterone replacement therapy, long-term anabolic steroid use, cancer medications (chemotherapy), certain antifungal and antibiotic medications, some ulcer medications and other medications can impair sperm production and decrease male fertility. Prior surgeries. Certain surgeries might prevent you from having sperm in your ejaculate. Sperm Production. In humans, spermatogenesis takes place in the seminiferous tubules, which are an intricate system of tubules in the testes where spermatogenesis takes place. The seminiferous tubules of an adult human male can sometimes produce over million sperm per day. Sperm Cell Precursors. In order to produce such a huge .

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